There is a 100% money back guarantee on all LifeWave products, so please
try them out for yourself and let us know how things go. I am always available
for any questions or concerns that you may have.
Energy patches provide a person with an immediate 20% - 40% or
more increase in strength endurance and enhanced physical and mental
energy. The LifeWave Energy Patches do this without putting anything
into the body. Instead, via the body’s electro-magnetic circuitry,
the patches electronically direct your cells to increase their
production of ATP... achieving much higher energy output. What
occurs at a cellular level... translates into greater energy,
strength and endurance overall because it is multiplied by billions
of cells. THE ENERGY PATCHES REALLY DO WORK!
Actually, the energy patches are more than safe... they are
healing and beneficial. According to Chinese acupressure healers...
the Energy Patches help balance the electrical energy of our body...
and counter negative electrical energy. You can quickly prove to
yourself that Energy Patches help neutralize harmful electromagnetic
fields and put your body into a stronger, better electrical mode.
Click here to view a video demonstration. LifeWave Energy Patches
have been worn by many people daily for over five years, with
exceedingly positive results. The list of who’s using the patches is
a list of the smartest people in the world and is growing daily.
LifeWave energy patches come as two patches in a set—a positive
(white) and a negative (tan) patch. These patches are worn on
opposite sides of the body... at meridian points on the body (such
as chest, wrists, knees and ankles). It is recommended to wear the
patches for up to 12 hours... every other day... or four days on and
then three days off, whichever way you prefer.
One feels nothing from wearing the patches... however... the amount
of energy one can expend before tiring is often nearly doubled...
quite an interesting phenomenon.
In reviewing how you can fully benefit from Energy Patches we
provide the following tips:
1. You won’t feel different. There is no feeling whatsoever to
wearing the energy patches. Specifically, there isn’t any buzz or
stimulated feeling. You will just be able to do more before your
muscles tire out. This is the most surprising aspect of the Patches.
No feeling... but instead of being stopped by muscle or energy
failure at a certain point... you can go beyond that previous
failure point easily.
2. how_to_wear_patches Energy pathways are often compromised
by injuries or toxic build-ups in the body that interrupt the flow
electro-magnetic energy through the meridians of the body. Energy
Patches will first try to revitalize these pathways. Once the
pathways are working properly, they will be able to effectively
communicate to your cells. If you don’t find any improvement in
strength endurance when wearing the patches at one matching set of
meridian points, we suggest you try other points. In fact,
experimenting in the locations of the patches is a good thing to do
in order to make sure all your pathways are working well. First, try
them on the chest/shoulders, then on the forearms, then on the
knees, then on the ankles... then back to the chest/shoulders. You
can also experiment with the back, stomach and backs of the calves,
if you wish, perhaps after consulting a picture of the body’s
hundreds of meridian points.
3. Wear the patches from morning until going to bed. Then skip a
day... (or you can do four days straight with patches on then take
three days off).
4. When locating the patches... find areas that produce greater arm
muscle strength. Even a half inch can make a difference. You can’t
locate the best spots in any other way than experimentation.
Answer by David
Schmidt, inventor of life wave energy patches.
One of the most common questions that people ask me is “How did you
come up with this incredible technology”? So, I will share my story
with you.
Began inventing at 8
years old
I was about 8 years old when I built my first robot; well, I don’t
know how good of a robot it was, but it was remote controlled, able
to move back and forth, and have some basic movements. Not bad
considering that I had been able to build almost all of it from my
brother’s race car set. Upon showing my creation to my father he
said, “Wow Dave that’s pretty good, but what did you make it from”?
When I gave him my answer he suggested that I put my older brother’s
race car set back together before my brother came home unless I
wanted some real trouble. So began my life as an inventor.
Got a programming
degree
I went on to get my degree in Management Information Systems only to
discover after 4 years of higher education that I really did not
want to be programming computers the rest of my life. So I did what
seemed to be the logical thing: I got a job designing medical
devices.
Changed professions to
medical device development
Say What? As it turned out, my mentor and friend owned a small
medical device development business in New Jersey and was willing to
take me on to teach me how to do research and development. Most of
the time I was creating problems from not knowing what I was doing,
however after about a year at this I decided to go back to school to
get a degree in Biology as it now appeared that I was on the right
track as far as my future was concerned.
Back to first love —
Inventing Things
Fast forward 10 years. I am now living the Atlanta, GA area and as
opportunity would have it I decide to join up with a local inventors
club called “The Inventors Clubs of America” owned and run by Dr.
Alex Marinachio. Dr. Alex becomes immediately intrigued with my
inventions and we become fast friends. He nominates me for an award
to the International Hall of Fame and I receive an Advanced
Technology Award for my invention of “Sea-Ment” a catalyst for
forming a new type of cement based on sea water. As a result of
receiving this award I am approached by a group interested in taking
my inventions to market. The deal sounds good so I join this North
Georgia think tank and off we go.
The reason why I accepted this opportunity was because some of the
people that I had a chance to work with came out of star wars
missile defense and other military projects. We were designing new
technology for both commercial and military applications.
Invents an amazing
oxygen generator
One of the new technologies that I
invented was a new type of Oxygen generator for the emergency
production of Oxygen. As an example, on a submarine - in the event
that the Nuclear Reactor needs to be taken offline - the crew must
resort to a device called a chlorate candle for producing breathable
Oxygen gas. The problem with these “candles” is that they are not
very efficient, produce toxic and dirty fumes, and once you light
them you cannot put them out. What I came up with was anew method
for producing Oxygen gas. As a comparison, if you look at the 35 lb.
cylinder that fireman use to get 30 to 60 minutes of air, my device
was the size of a can of Coke yet could product about 4 hours of
Oxygen! Needless to say, I produced an “impossible device that drew
the attention of all who saw it.
Asked to help with a
Navy Seal project
Then
one day I received a call from someone who is a well respected
Nuclear Engineer at a well known government contractor. He said to
me that he had been impressed with my group’s out of the box”
thinking and that he wanted to invite me to participate in the
design of the Navy’s next generation submarine, a new class of
mini-sub.
Now
a mini-sub for the Navy is something about 60 feet long! What was
interesting about this project was that this sub was going to be
manned by Navy Seals, and because of the nature of the missions it
would be highly desirable to find ways to improve the crews
survivability. There were delays in getting this project started so
I never officially joined, however there were certain aspects of
this project that intrigued me. For example, the Navy frowned upon
stimulants, energy drinks, pep pills, etc. so none of this would be
permitted on the mini-sub. In addition (as you can probably imagine)
space is a premium on a mini-sub, so anything that can improve
survivability would have to be small, compact and light.
Starts thinking about
“out of the box” ways to make the human body program itself to be
more survivable, stronger and better functioning
Then, the moment that every inventor loves hit me: the thought
occurred to me that we have wireless communication today in the form
of cell phones and satellite TV; why not have a way to wirelessly
communicate with the human body. A device that could “talk” to the
body to ask the body to do different things.
If you could talk to your body, what would you ask it to do? Would
you ask your body to make your muscles bigger? How about improve
your energy and stamina? Make you smarter? Stronger? Lose that extra
body fat? Well, I think you get the idea. But is such a thing
possible? Doesn’t this sound a bit like science fiction? I mean,
after all, how could any device “talk” to our body, with the body
following these instructions?
Well, as it turns out, there IS a way to do it, and that’s what
the LifeWave technology is all about!
Explanation about
human electromagnetic fields, which are the key to “talking” to our
body’s cells
Back
in the early 1980’s a scientist in the United States named Dr. John
Zimmerman was using a device known as a SQUID magnetometer ( a giant
coil of wire that is superconducting) to detect very small pulsating
magnetic fields directly above the surface of the human body. The
magnetic fields were so small (pico-tesla range that the SQUID that
he used consisted of about 2,000,000 turns of wire! But the
important thing was the he DID find that the human body did emit
pulsating magnetic fields. But where did these magnetic fields come
from?
Do
you remember in high school when you learned that electrons flowing
through a wire/conductor produced magnetic fields at right angles?
Well guess what is flowing through our bodies all of the time?
Electrons! And isn’t our body a conductor of electricity? Those
electrolytes must be doing something electrical! Not to mention how
nerve impulses travel from the brain to the muscles in our bodies.
OK,
so we have a pulsating magnetic fields around us, so what? How could
we use this knowledge for any type of benefit? Well, when was the
last time you used a radio? Do you remember seeing something that
said AM of FM? This stands for Amplitude Modulation and Frequency
Modulation (respectively) but is a fancy way of saying that we take
a high frequency carrier wave and modulate it so that we can encode
information on the wave.
Then
there is a little thing called resonant energy transfer. Did you
ever throw a stone in a lake and watch the stone create ripples? or
did you ever surf on the north shore of Hawaii? Those big waves can
actually form from earthquakes in Alaska! That’s resonant energy
transfer and it is the process by which energy is moved from one
place to another in a resonant fashion. For example hold one end of
a rope and give the other to someone else to hold. Now start to
create a “wave “ in the rope; the wave will travel from one end of
the rope to the other. This is resonant energy transfer.
One last lesson and then on to LifeWave!
Did
you ever wonder how the human body is able to detect things like
free radicals and send antioxidants to stop them? This is known as a
proceed called signal transduction, and without getting into the
biochemistry this is the process by which biochemical messages are
sent between the cell nucleus and other parts of the cell. Suffice
ti to say that the DNA in the cell is able to send receive messages,
however this process is typically thought of as being a biochemical
process rather than an electronic process.
Now, enter LifeWave!
What
I was able to do was to invent a method by which I could “program”
organic structures the same way that we program computer chips! I
started with ordinary materials like amino acids and specific sugars
(I only work with materials that the FDA lists as safe and things
that people at) and put them into water-based solutions. I then
process these materials in a very special way so that they are
capable of “talking” to the human body. The amazing thing about the
LifeWave patches is that NOTHING enters the body; instead, we have a
patch that communicates with the body to cause different things to
happen. In the case of LifeWave energy patches what we find is that
within minutes of using the patches there is a dramatic gain in
stamina. Because LifeWave IS NOT a stimulant, you will “feel” this
increase in energy no jitters or energy rush) but just go ahead and
do a workout and you will find that you will not get as tired or
fatigued - Do you feel food being converted into energy - LifeWave
is a similar phenomena).
Launching
a company to share nanotechnology patches that instruct the body how
to be stronger, faster and have more energy!
After developing this radically new
technology, David Schmidt has been trying to financially capitalize
on this technology in the best way possible for the past several
years.
He has also been working on new
applications of his biological signaling amino acid patches. These
new applications that will be made available to the public in 2005
include:
Sleep
patches
HGH stimulating patches
Muscle tissue growing patches
So far in David’s efforts to get
the marketing of this new technology going... beginning with the
energy patches, there have been two false starts with network
marketing companies. Numerous companies have offered to buy the
technology outright from Dave... but he doesn’t want this.
With the final company launch of
LifeWave in 2004... enrollments began in November, product is
shipping in late November and it all looks good. LifeWave is going
to be the fastest launch of any networking company ever... because
it is something new and phenomenal that can proved instantly. No one
without Energy Patches will be able to compete against those with
them. Everyone who wants to feel young and energetic will appreciate
them.
Yes, they have been tested by the
United States Anti-Doping Agency (USADA) and it has been verified by
this agency that nothing
physical enters the body. The paches have been
approved for Olympic competition and the energy patches were
used in training and competition by many of our United States
Olympic swimmers in 2004, including Michael Phelps. All materials in
the Energy Patch are listed by the FDA as completely safe... under
21 CFR. The Energy Patch is manufactured at FDA registered
facilities.
significant increase in one’s
capability for physical exertion
much more rapid recovery after
exertion
With Energy Patches... you won’t
tire as rapidly... so you can walk further... dance
longer... and enjoy yourself more.
In reviewing what
seniors must do to fully benefit from Energy
Patches we provide the following tips:
You won’t feel different.
There is no feeling whatsoever to wearing the energy patches.
You just have more ability to do... You will have to
prove it to yourself by seeing how much more you can exert
yourself.
It
may take a while for the energy to kick in.
Electro-meridian energy pathways are often compromised in senior
citizens. Energy Patches will first
revitalize these pathways... and then begin to
effectively communicate to your cells. Therefore, we suggest
utilizing all four of the major meridian points— rotating from
one point to the next for the first month. In other words, wear
the patches on the chest/shoulders, then on the forearms, then
on the knees, then on the ankles... then back to the
chest/shoulders. You can also experiment with other meridian
points in the back, stomach and backs of the calves, etc. This
will revitalize your body’s circuitry. You may feel like you are
wasting the patches... since the energy increase won’t be felt
unless your pathways are working properly. But, doing this is
worth it. The more you use the Energy Patches...
the better they will work.
Wear the
patches from morning until going to bed. Then skip a day... (or
you can go four days with patches on then three days with the
patches off).
Keep in mind,
when trying to locate the patches on your body that you are
trying to locate unblocked electromagnetic meridian juncture
points in your body. These meridians transport the signal from
the patches. With this in mind:
Experiment by using different
locations... until you find the best
locations for you. (You will only be
able to tell if you muscle test... for
strength and endurance... or just go
about your day... and see if you can
accomplish more.)
And, utilize muscle testing to find your
strongest points... these are the
locations best suited for placing the
energy patches.
Here are testimonials from seniors
regarding the patches:
Marvin Barre, Atlanta Executive says, “My wife and I have
been using the LifeWave patches for a year now, and getting super
results. We like to wear them daily for energy, especially if we have strenuous
activities to do, like painting and yard work.
I always wear them when playing golf.”
Tony Berto Retired HS Hall of Fame Football Coach, Delphi,
Indiana says, “Before wearing the LIFEWAVE patches, I thought my
days of being an active and productive adult were over. Bad
circulation in both legs kept me from participating in the
activities I used to take for granted. Soon after I started wearing
the patches, I began to feel much better. I am doing things now that I only used
to do 10 years ago. I’ve
noticed a huge difference in my attitude and outlook for the future.
It’s wonderful to feel this good again, and I attribute it to the
extra energy that the LIFEWAVE patches have given me. Thank you very
much.”
Barry Williamsl, says, "I have to tell you two amazing
stories from my mother, Rita Williams. She is 78 years old and just
had 5 way by-pass surgery.
First she said she needed to increase her leg strength and was
starting to ride a stationary bike, I sent her some patches and told
her to use them after her normal ride. She called and said she
normally did 1/4 mile. Afterwards she waited for ten minutes, put on
the patches, and did one whole mile.
But then she called me again last night and told me the most heart
warming story:
Mom confessed that since her new grandson was born 8 months ago she
has not been able to pick him up (20 lbs), so she was limited to
someone passing the baby to her while she was sitting down. But
yesterday when Amy brought the child over, she decided to put on the
patches. She proceeded to not only pick the baby up from the crib;
she carried him around for another hour. “And I didn't get tired at
all". She said it was the best day
of her life and why had I not sent her more patches?
I promised to send more immediately.
"It was like I was at least 10 years younger."
Eric Robinson, San Jose, Costa Rica says, "I am the reining
Latin American and Caribbean Over-All Masters Swimming Champion in
the 50 to 54 year class. I was very skeptical of the LIFEWAVE
patches, but now I swear by them.
When I don't have a patch on, I feel lethargic, and lazy,
and find in workouts it is much more difficult physically and
mentally to maintain a high level of effort. Without the patches my
muscles get heavy, and my arms start to feel like rubber in a short
period of time. With the patch I can take a week or two off and
climb back into the pool, and pick up right where I left off, they
are amazing! You don't get tired easily, even doing butterfly! Being
a Masters Swimmer at 52 years old, the LIFEWAVE patches just came
along in time. I hope my competition doesn't discover them before I
go to the Worlds in 2007!"
Jerry McGee, Tour Professional, Champions Tour, Senior PGA ,
says, “I really love them. I used the patches everyday in my last
event, which was a major and I could definitely tell a difference.
My energy was great and I felt terrific. Since then, I’ve also
started wearing them when I practice. Thanks so much.”
far less lactic acid buildup in muscles
for less soreness... and in many cases, almost instant recovery
after exertion
A review
for athletes, excerpts by Dr.
Steven Haltiwanger, MD CCN
LifeWave Energy Patches are much
more powerful than supplements such
as Creatine, Glutamine or protein powders or any other supplement.
An athlete in competition would have little
chance in a real life match-up against a man or woman
using the LifeWave technology.
LifeWave is also safer and more effective to use for performance
enhancement than steroids.
With the Energy Patches you will be able
to reach new levels of energy and stamina within 1 week that
would normally take months
of intense training to achieve. And, if you are competing, you can
devastate another athlete by not
becoming as tired, fatigued or worn out.
You can demonstrate to yourself
improvements in energy and stamina that are so fast it is almost
impossible to believe. You can achieve these results regardless of
age, sex or race. You can use the LifeWave Energy Patch technology
as often as you like to achieve your own desired level of
performance. You can use the Energy Patches in competition—many
people already have done this to outperform and outlast everyone
else.
Supplements like Creatine and Glutamine
require at least a few weeks before any noticeable improvements in
strength or stamina can be seen. Energy Patches start to work in
minutes, and measurable increase in energy and stamina can be
demonstrated in as little as 10 minutes. The Energy Patches are only
enhanced by hydration and good nutrition. Here are some examples of
results:
Examples
One man who tried the Energy Patches
normally worked out with 185 lbs. in the Bench Press for 8 reps.
With the Energy Patches he was able to do 14 reps—a 75% increase in
pure stamina within a few minutes.
A teenager who participated in our tests
usually Bench Pressed 150 pounds for 12 reps and was not able to do
13 reps. He used the Energy Patches, and after only 10 minutes was
able to do 21 reps—again a 75% increase in strength and endurance
within just a few minutes.
Two
Surprise Benefits of the Energy Patches
Confidence and Peace of Mind -
you will no longer fear the competition.
More Energy throughout your
entire day.
Getting
that 5% Increase in Stamina
Statistics show that there is less than
5% difference in performance between those athletes that “make it”
and those that don’t. Think about it. when you watch the Olympics,
there is less than 1 second that separates the first place Gold
medal winner from the losers in timed competitions. And these
athletes train for 4 years to compete in these events! Wouldn’t
haveing more stamina, more energy from the Energy Patches make a
difference? They do. Energy Patches have in double blind studies
produced
34% to
69% improvements in muscle
endurance or stamina.
Athletes
who are using the Energy Patches
Many members of
the USA swimming team used the Energy Patches in training for
this year’s 2004 Olympics held in Greece, including Michael
Phelps.
Many of the top
competitors in the Arm Wresting Championship held in October of
2004 used the Energy Patches.
Mr.
Ronnie Coleman, 7 times winner of
Mr. Olympia, is an official endorser of the Energy Patches.
Also,
JoAnne Carner, LPGA Tour Hall of Fame Professional uses
and endorses the Energy Patches from LifeWave.
Here’s a statement from a strength
and conditioning trainer regarding the Energy Patches:
Mike Gailey, Former Professional Soccer Player, Certified
Strength and Conditioning Specialist, says,
“I wanted to write you a testimonial about my experience with the
LifeWave Patches. I am a former professional soccer player and have
been a personal trainer for 12 years. I am amazed at the exercise
endurance I get when I wear the patches. Let me give you my first
day experience with the patches and you will see what got my
attention.
I played tennis for 2 hours in the morning, went home and lifted
weights, cut my lawn, ran with my 4 dogs (1 at a time), cleaned my
house and ran with my dogs again without any drop in energy! I could
not believe the difference the patches made. Since then, I have used
them when I play tennis and when I lift. People always ask me how I
do all the things I do in one day and I tell them the answer is
simple, LifeWave.
I also would like to give some of the experiences I have had with my
personal training clients:
77.2% increase in leg strength in a 4 week period for 2 of my
clients (week 1 without patches and 3 weeks with them).
My clients are gaining between 30% and 77% strength monthly.
One client lost 7pounds in the second week she wore the LifeWave
patches.
Every client is amazed at the great feeling they get when they wear
the patches! I just thought you should know how much my clients and
I love the LifeWave patches."
Quick Recovery from Exertion:
Russia’s Olympic doctor (who uses
cutting edge technology to measure athlete’s recovery from exertion
times) was blown away to discover that their athletes who used the
Energy Patches had recovery times after maximum exertion that were
less than a minute as compared to several hours without the Energy
Patches.
No Buzz, No Drugs, No
Stimulants:
LifeWave Energy Patches provide
nearly boundless energy and stamina. They help you to feel great all
the time. They don’t provide this energy in a stimulative way. There
is no caffeine buzz... followed by a crash. With the Energy
Patches... nothing enters the body. Instead a tiny electromagnetic
signal instructs your body’s cells through the natural
electro-meridian circuitry of the body to burn fat for energy. Too
simple... GREAT THINGS ARE SIMPLE.
The
technology really works. It works almost immediately and it
allows you to accomplish more than ever before. Listen to the
following audio testimonials and try the Energy Patch today.
·
Glutathione (pronounced "gloota-thigh-own") is the body's essential
health AID - Antioxidant, Immune booster and Detoxifier. This small
protein, produced naturally in the body, maintains these three
crucial protective functions. In fact, your life depends on
glutathione. Without it, your cells would disintegrate from
unrestrained oxidation, your body would have little resistance to
bacteria, viruses and cancer, and your liver would shrivel up from
the eventual accumulation of toxins.
·
Glutathione is not yet a household word. Even doctors who have heard
the term may have only a vague idea of it. However, everyone will
soon be talking about this critical substance. There was a time when
only scientists had heard of cholesterol and vitamins, but today
everyone knows about them. Now it's glutathione's turn. In the last
five years, over twenty-five thousand medical articles about this
substance have been published, and this scientific understanding is
gradually becoming common knowledge.
·
Each and every cell in the body is responsible for its own supply of
glutathione, and must have the necessary raw materials to make it.
Glutathione is always in great demand and is rapidly consumed when
we experience any sort of pressure - illness, stress, fatigue and
even exercise. Glutathione levels also diminish as we age and any
diseases associated with aging have been linked to glutathione
deficiency.
Why Glutathione is Essential to
Health
Glutathione's three major roles in the body
are summarized by the letters A-I-D -Antioxidant, Immune booster,
and Detoxifier- three critical processes driven by glutathione.
The Master Antioxidant (AID)
Over the past thirty years researchers have
explored the value of antioxidants in good health, as well as the
treatment and prevention of diseases involving oxidative attack by
free radicals. This has produced a whole new branch of medicine -
Free Radical Biology. Free radicals have been implicated in all
sorts of illness, including heart disease, cancer, diabetes and
aging itself.
Well-known and widely used antioxidants such as vitamin C, vitamin E
and selenium neutralize free radicals. They occur naturally in
nature, but not in the body - they must be introduced as part of a
balanced diet. Given the critical role of antioxidants in good
health, it is not surprising that the body itself manufacturers its
own natural antioxidants. The most import of these is glutathione.
Because all other antioxidants depend upon the presence of
glutathione to function properly, scientists call it "the master
antioxidant."
Food for the Immune System (AID)
The immune system's function is to identify
and attack germs and other invaders, including cancer cells. A body
with plenty of glutathione fights off these threats more easily by
denying most of them a foothold and by confronting the few that get
through with an enhanced immune system. Elevated glutathione levels
enable the body to produce more white blood cells - the most
important front line defense of the immune system.
Glutathione plays a central role in the functions of these immune
cells. Dr. Gustavo Bounous, a leading glutathione expert says, "The
limiting factor in the proper activity of our lymphocytes (white
blood cells) is the availability of glutathione." In other words,
healthy growth and activity of immune cells depend upon
glutathione's availability. Put simply, glutathione is 'food' for
the immune system.
Natural Detoxification (AID)
Whether we know it or not, we are continually
inhaling and ingesting natural and synthetic toxins. They are
unavoidable in these modern times, both in our polluted cities and
our engineered food supplies. When the body has its health and the
nourishment it needs it works tirelessly to eliminate toxins and
protect itself, but increasing levels of environmental pollution are
depleting its stores of glutathione more and more rapidly. Our main
organ of detoxification is the liver - the body's most concentrated
source of glutathione. Studies show that low glutathione levels lead
to poor liver function, causing more and more toxins to circulate
through the body and resulting in damage to individual cells and
organs. Doctors routinely use glutathione-promoting drugs to
detoxify victims of certain types of drug overdose.
LINKS and REFERENCES:
Glutathione: Systemic Protectant
Against Oxidative and Free Radical Damage
Parris M. Kidd, Ph.D.
Whey proteins in cancer prevention
Bounous G, Batist G, Gold P.
Measurement of Glutathione (GSH) as
Indicator of Immune Status:
Patrick, C.W., DeLeon, M., A. Leon, and Keller, R.H. -Conference on
Clinical Laboratory Testing in HIV, Atlanta, GA 1998.
The use of a whey protein concentrate
in the treatment of patients with metastatic carcinoma: a phase I-II
clinical study
Kennedy RS, Konok GP, Bounous G, Baruchel S, Lee TD.
Stanford NAC Study: Glutathione Level
Predicts Survival
John S.James
The Role of Glutathione
·
"We literally cannot survive without this miraculous antioxidant,"
according to Dr. Earl Mindell, What You Should Know about the
Super Antioxidant Miracle
·
"Without glutathione, other important antioxidants such as vitamins
C and E cannot do their job adequately to protect your body against
disease." Breakthrough in Cell Defense, Dr. Allan
Somersall, Ph.D., M.D. with Dr. Gustavo Bounous, M.D. FRCS(C)
·
"No other antioxidant is as important to overall health as
glutathione. It is the regenerator of immune cells and the most
valuable detoxifying agent in the body. Low levels are associated
with early aging and even death." The Immune System Cure,
Lorna R. Vanderhaeghe & Patrick J.D. Bouic, Ph.D.
·
"Your life depends on glutathione. Without it, your cells would
disintegrate from unrestrained oxidation, your body would have
little resistance to bacteria, viruses and cancer, and your liver
would shrivel up from the eventual accumulation of toxins."
Glutathione: Essential Health AID - Antioxidant. Immune
Booster. Detoxifier, Dr. Jimmy Gutman, MD, FACEP
·
"A review article published in the Annals of Pharmacology
stated that glutathione is important in DNA synthesis and repair,
protein and prostaglandin synthesis, amino acid transport,
detoxification of toxins and carcinogens, enhancement of the immune
system, and protection from oxidation and enzyme activations." The Immune System Cure, Lorna R. Vanderhaeghe & Patrick
J.D. Bouic, Ph.D.
·
"Glutathione has potent anti-viral properties - if you raise the
glutathione level you can stop the replication of most any, at
least, intracellular pathogen....but glutathione deficiency produces
a pro-viral effect." Dr. Paul Cheney, transcribed from a workshop
presentation on
the clinical management of Chronic Fatigue Syndrome
·
"Glutathione levels also diminish as we age and many diseases
normally associated with aging have been linked to glutathione
deficiency." Glutathione: Essential Health AID - Antioxidant.
Immune Booster. Detoxifier, Dr. Jimmy Gutman,
MD, FACEP
·
"Clinical evidence links low glutathione levels to the most common
illnesses of our time as well as newly emerging diseases."
Glutathione: Essential Health AID - Antioxidant. Immune
Booster. Detoxifier, Dr. Jimmy Gutman, MD, FACEP
·
"Because all other antioxidants depend upon the presence of
glutathione to function properly, scientists call it 'the master
antioxidant'." Glutathione: Essential Health AID - Antioxidant.
Immune Booster. Detoxifier, Dr. Jimmy Gutman,
MD, FACEP
·
"Healthy people also benefit from elevated glutathione levels
through an enhanced ability to fight off toxins, infectious disease,
pre-cancerous cells and the aging process itself."
Glutathione: Essential Health AID - Antioxidant. Immune
Booster Detoxifier, Dr. Jimmy Gutman, MD, FACEP
·
Many world-class athletes are discovering that well-maintained
glutathione levels give them the edge over their competitors,
bringing greater strength and endurance, decreased recovery time
from injury, less muscle pain and fatigue, and muscle-promoting
activity." Glutathione: Essential Health AID - Antioxidant.
Immune Booster. Detoxifier, Dr. Jimmy Gutman,
MD, FACEP
·
It is well known that aging is accompanied by a precipitous fall in
glutathione levels. Lower glutathione levels are implicated in many
diseases associated with aging, including cataracts, Alzheimer's
disease, Parkinson's, atherosclerosis and others. Journal of Clinical Epidemiology 47: 1021-26 1994
·
Low glutathione levels have been associated with neuro-degenerative
diseases such as MS (Multiple Sclerosis), ALS (Lou Gehrig's
disease), Alzheimer's disease and Parkinson's disease, among others.
The Lancet 344: 796-798, 1994
·
Glutathione plays a role in eliminating many carcinogens and also
maintains an optimized immune function, providing stronger
anti-tumor defenses. Cancer Letters 57: 91-94 1991
·
Low glutathione levels correspond to poor survival in AIDS patients.
Much documentation demonstrates the role of enhanced glutathione
levels in AIDS. Proceedings of the National Academy of Science, USA 94: 1967-72,
1997
·
Raised glutathione levels fight the oxidation of circulating fats in
the bloodstream, including cholesterol, retarding the process of
plaque formation in the arteries - the underlying cause for most
heart disease and stroke. Nutrition Reviews 54: 1-30, 1996
·
Diabetics are prone to infections and circulatory problems leading
to heart disease, kidney failure and blindness. Glutathione protects
against the complications of diabetes. Clinical Science 91: 575-582, 1996
·
Doctors have used glutathione-promoting drugs to treat many lung
diseases including asthma, chronic bronchitis and emphysema. Newer
potential therapeutic roles can be found for cigarette smoke damage,
pulmonary fibrosis and other illnesses. American Journal of Medical Science 307: 119-127, 1994
·
Glutathione protects the body from the inflammation of gastritis,
stomach ulcers, pancreatitis and inflammatory bowel disease
including ulcerative colitis and Crohn's disease. Gut 42: 485-492, 1998
·
The liver is the major storehouse for glutathione. Glutathione is
impaired in alcoholic hepatitis as well as in viral hepatitis A, B,
and C. Raised glutathione levels restore liver function. American Journal of Gastroenterology 91: 2569-2573, 1996
·
Glutathione detoxifies a variety of pollutants, carcinogens and
poisons, including many found in fuel exhaust and cigarette smoke.
It also retards damage from radiation exposure due to the eroding
ozone layer. Annual Reviews of Biochemistry 52: 711-760 1983
● Multiple Chemical Sensitivity
(MCS) -- It has been found that MCS patients exhibit the lower than
normal levels of glutathione, the bodies major detoxification
chemical, that is also characteristic of chronic fatigue syndrome,
fibromyalgia, gulf war syndrome and autism. Low glutathione would
result in poor detoxification and excretion of toxic chemicals,
leaving them in the blood stream and tissues where they could cause
cellular damage and interfere with biochemical processes.
·
Raised glutathione levels help increase strength and endurance.
Those interested in physical fitness can benefit from a definite
athletic edge. Journal of Applied Physiology 87: 1381-1385, 1999
·
Strong muscular activity, such as that experienced by athletes,
generates oxyradicals [free radicals] leading to muscle fatigue and
poorer performance. Glutathione neutralizes these radicals. Sport Medicine 21: 213-238, 1996
·
Lymphocytes, cells vital for your immune system, depend on
glutathione for their proper function and replication. IMMUNOLOGY 61: 503-508 1987
·
Antioxidants are well documented and known to possess vital roles in
health maintenance and disease prevention. Glutathione is your
cell's own major antioxidant. Maintaining elevated glutathione
levels aids the body's natural antioxidant function. Biochemical Pharmacology 47: 2113-2123 1994
What is Glutathione (GSH)?
Glutathione, or GSH, is a naturally occurring
protein that protects every cell, tissue, and organ from toxic free
radicals and disease. It is a tripeptide of three amino acids -
glycine, glutamate (glutamic acid), and cysteine. These precursors
are necessary for the manufacture of glutathione within the cells.
Find Out More About Glutathione
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press the "Search" button. By entering the word “glutathione”, a
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This article will
demonstrate to you why Glutathione is so
important to your health and well-being.
Glutathione (pronounced 'gloota-thigh-own') is the body's
essential health
ABC's - Antioxidant, Blood Booster and Cell Detoxifer.
It is a tripeptide composed of glutamic, cysteine and glycine.
Glutathione
is found in all cells in the body, including the bile, the
epithelial lining
fluid of the lungs, and - at much smaller concentrations - in the
blood.
Glutathione is the smallest intracellular non-protein thiol
(molecule
containing an S_H or sulfhydryl group) molecule in the cells. This
characteristic emphasizes its potent antioxidant action and supports
a
multifaceted thiol exchange system, which regulates cell activity.
This small protein, produced naturally in the body, maintains
these three
crucial protective functions.
In fact, your life depends on glutathione. Without it, your
cells would
disintegrate from unrestrained oxidation, your body would have
little
resistance to metabolic acids, and your liver would shrivel up from
the
eventual accumulation of acidic toxins.
Glutathione is not yet a household word. Even some medical and
holistic
doctors who have heard the term may still have only a vague idea of
what it
is. However, everyone will soon be talking about this critical
non-nutritive substance.
There was a time when only scientists had heard of cholesterol and
vitamins,
but today, everyone knows about them. Now the magnificence of
glutathione
is becoming known.
In the last five years, over 25,000 medical articles about this
substance
have been published, and the scientific understanding of glutathione
is
gradually becoming common knowledge.
Each and every cell in the body is responsible for its own supply
of
glutathione and must have the necessary raw materials in order to
produce it.
Glutathione is always in great demand and is rapidly consumed when
we
experience any sort of emotional or physical stress, fatigue and
even
moderate exercise.
Some well-known causes of glutathione depletion are as follows:
1) Acidic lifestyle and diet
2) Air and Water pollution
3) Prescription and recreational drugs
4) Ultraviolet and Radiation from cells phones, computers,
electrical cars,
power lines, hair dryers, etc.
5) Emotional and physical stress
6) Injury, trauma or burns
7) Heavy metals
8) Cigarette smoke
9) Household chemicals
10) Acetaminophen poisoning
11) Exhaust from motor vehicles
12) Septic shock
All of these above factors lead to a build up of acidic toxins that
cause
the loss of glutathione as a non-nutritive buffer leading to
cellular aging,
disease and finally death.
Why is Glutathione Essential to Health?
Glutathione's three major roles in the body are
summarized by the letters
A-B-C.
- Anti-oxidant
- Blood Booster
- Cell Detoxifier
These are the three critical processes driven by glutathione.
The Master Antioxidant
Over the past thirty years, researchers have explored the role of
antioxidants in good health as well as the treatment and prevention
of
diseases involving oxidation or fermentation by metabolic acids.
Well known and widely used antioxidants such as vitamin A, vitamin E
and
selenium neutralize acid. They occur naturally in nature, but not
in the
body. They must be introduced as part of a balanced diet.
Given the critical role of antioxidants
in good health, it is not surprising that the body itself
manufactures its
own natural antioxidants.
The most important of these is glutathione. Because all other
antioxidants
depend upon the presence of glutathione to function properly,
scientists
call it 'the master antioxidant.'
Glutathione binds to toxins, forming a water-soluble complex
- which is
ultimately excreted in the urine or bile as waste.
Food for the Blood
Elevated glutathione levels enable the body to produce more white
blood
cells. White blood cells are the body's garbage collectors and are
the most
important cells for maintaining sterility of the body fluids.
Glutathione plays a central role in the proper function of the white
blood
cells. Dr. Bustavo Bounous, a leading glutathione expert, says,
'The
limiting factor in the proper activity of our lymphocytes (the white
blood
cells) is the availability of glutathione.' In other words, healthy
growth
and activity of the white blood cells depends upon glutathione's
availability. Put simply, glutathione is 'food' for the white
blood cells.
Cellular Detoxifier
Whether we know it or not, we are continually inhaling and ingesting
natural
and synthetic acidic toxins. They are unavoidable in these modern
times
both in our polluted cities and our poorly engineered food
supplies. When
the body has the health and the nourishment it needs, it works
tirelessly to
eliminate acidic toxins and to protect itself. But, increasing
levels of environmental pollution are depleting the body's store of
glutathione more and more rapidly. Our main organ of detoxification of acidic waste products is the
lymphatic
system and the liver. This is the body's most concentrated source of
glutathione.
Studies show that low glutathione levels lead to poor lymphatic
and liver
function, causing more and more acidic toxins to circulate
through the body
and resulting in damage to individual cells and organs.
Medical doctors today routinely use glutathione- promoting drugs to
detoxify
victims of certain types of drug overdose.
Glutathione in Natural Medicine
Practitioners of complementary and alternative medicine (CAM) have
long
advocated the use of milk thistle for liver problems. It
turns out that
this herb works by modestly elevating glutathione levels. The
mineral selenium also produces subtle elevations in glutathione by
becoming
integrated into the glutathione peroxidase.
Emergency medical doctors, toxicologists and lung and liver
specialists are
well acquainted with glutathione's therapeutic uses. American
physicians
seeking ways to raise a patient's glutathione levels can open the
standard
Physician's Desk Reference
(PDR) and find two options - the pharmaceutical drugs sold under the
names
Parlodex and Mucomyst, and the natural dietary supplement found in
natural
foods stores derived from whey protein isolate.
Drugs That Raise Glutathione Levels
Pharmaceutical drugs like Procysteine, OTC, OTX, Glutathione
monoesters and
Glutathione diesters have been used to raise glutathione levels.
However,
they all produce side effects and are unsuitable for long term use.
This pharmaceutical non-nutritive chemical is used to break up mucus
in lung
diseases such as cystic fibrosis, chronic bronchitis and asthma.
It
remains the standard treatment for acetaminophen overdose.
It is believed that glutathione has an important role to play in
the
prevention and treatment of disease.
It may in the future be considered as important to health as an
alkaline
diet, exercise and alkaline lifestyle. Clinical tests show
that raised
glutathione levels may address some of the eight major health issues
of our
time:
1) Cardiovascular
- Prevents heart disease - Shimizu H, Kiyohara
Y, Kitazono T, Kubo M,
Ibayashi S, Fufishima M, Lida M.
Relationship Between Plasma Glutathione Levels and Cardiovascular
Disease in
a Defined Population: The Hisyama Study. Stroke. 2004 Sep;
35(9):2072-7. - Prevents stroke - Paterson PG, Juurlink BH.
Nutritional Regulation of Glutathione in Stroke.
Neurtox Res. 1999 Dec; 1(2): 99-112. - Prevents atherosclerosis - Coppola L, Grassia
A, Giunta R. Glutathione
Improves Haemostatic and Hemorrheological Parameters in
Atherosclerotic
Subject. Drugs Exp. Clin Res 1992
18:493-98
Cancer causing polychlorinated biphenyls (PCBs) have been found to
alter
levels of glutathione compounds in experiments, which may alter the
body's
resistance to certain types of cancer.
Glutathione deficiencies have been linked to many forms of
cancer.
- Prevents cancerous tissue
- Suppresses tumor growth
- Eliminates carcinogen - acids
- Retards oxidative stress
- Prevents wasting disease
- Eases side effects of chemotherapy and radiotherapy
3) Pulmonary
Glutathione is the most efficient free radical (acid) scavenger in
the
airways, and dozens of studies have confirmed that free radical
(acid)
damage is a primary player in Chronic Obstructive Pulmonary
Disease. Rahman
I, MacNee W. Oxidative Stress and Regulation of Glutathione in Lung
Inflammation. Eur Respir J. 2000 Sep; 16(3):534-54.
- Breaks up mucus - Rahman I, MacNee W.
Oxidative Stress and Regulation of Glutathione in Lung Inflammation.
Eur
Respir J. 2000 Sep;
16(3):534-54
- Cystic fibrosis - Glutathione neutralized harmful oxidants
introduced into
the lungs or those released by cells. Exotoxins from bacteria can
overload
the endobronchial terrain and feed the fires of acidic
inflammation. This
staggering burden increases the oxidative sensitivity of the CF
lung,
resulting in further injury of lung parenchyma. Data supports
evidence of a
decrease in the anitoxidant tri-peptide glutathione (Roum JH, Buhl
R,
McElvaney NG, et al.
Systemic Deficiency of Glutathione in Systic Fibrosis. J Appl
Physiol 1993; 75:19-24).
- Asthma - Chronic bronchitis
- Emphysema
- Lamson, David, MD, Grignall, Matthew, ND. The use of
Nebulized Glutathione in the Treatment of Emphysema: A Case Report.
Altern
Med Review. 5(5);429-431, 2000 Oct.
- Pulmonary fibrosis - Ishii T, Fujishiro M, Nakajima J,
Teramoto S, Ouchi
Y, Matsuse T. Depletion of Glutathion S-Transferase P1 Induces
Apoptosis in
Huamn Lung Fibroblasts. Exp Lung Res. 29(7);523-36, 2003 Oct-Nov.
4) Aging
Glutathione is critically important to our brain as it is one of
the most
important brain antioxidants. Glutathione helps preserve brain tissue by preventing damage
from free
radicals (acids).
In addition to quenching dangerous acids, glutathione also acts to
recycle
vitamin E which also has the ability to reduce acidity in the brain.
(Perlmutter D., BrainRecovery.com July 2004, 5th ed:13)
- Autism - Medical literature documents that an out-fection
can lead to a
lowering of glutathione which participates in detoxification,
interacts with
metallothioneins, and supports
many crucial aspects of immunity. A link
between glutathione and autism regression may derive from the fact
that
transient or chronic intestinal problems can impair an infant's or
toddler's
nutritional status, thereby minimizing the levels of amino-acids
required
for the production of glutathione (McCandless, J. Children With
Starving
Brains. 2003, 2nd ed;
252)
- Parkinson's Disease - Glutathione helps to preserve brain
tissue by
preventing damage from free radicals (acids) and destructive
chemicals
formed by the normal processes of metabolism, toxic elements in the
environment, and as a normal response of the body to challenges by
acidic
agents or other stresses. With the understanding that glutathione
is
important for brain protection and that this protection many be
lacking in
the brains of Parkinson's clients due to glutathione deficiency, it
can be
seen as very beneficial.
(Di Monte DA, Cahn P, Sandy MS. Glutathione in Parkinson's Disease:
A Link
Between Oxidative Stress and Mitochondrial Damage?
An Neurol. 32 Suppl; S111-115, 1992.)
- Alzheimer's Dis-ease - Woltjer, R.L., Hgheim W., Maezawa I.,
Vaisar T,
Montine K.S., Montine T.J., Role of Glutathione in Intracellular
Amyloid-Alpha Recursor Protein/Carboxy- Terminal Fragment
Aggregation and
Associated Cytotoxicity. J Neurochem. 2005 May; 93 (4): 1047-56.
- Huntington's DisEase - Choo Y.S., Mao Z, Johnson GV, Lesort
M. Increased
Glutathione Levels In Cortical Striatal Mitochondria of the
R6/2 Huntington's Disease Mouse Model.
Neuroscience Letter. 2005 Sep 23; 386(1): 63-8.
- Multiple Sclerosis - Calabrese V, Scapaginini G, Ravagna A,
Bella R,
Butterfield DA, Calvani M, Pennisi G, Giuffrida Stella AM.
Disruption of
Thiol Homeostasis and Nitrostative Stress in the Cerebrospinal Fluid
of
Patients with Active Multiple Sclerosis: Evidence for a Protective
Role of
Acetylcarnitine. 2003 Sep; 28(9):
1321-8. Mann CL, Davies MB, Aldersea J,
Fryer AA, Jones PK, Ko Ko C, Young C,
Strange RC, Hawkins CP. Glutathione
S-Transferase Polymorphisms in MS:
Their Relationship to Disability. Neurology.
2000 Feb 8;54(3):542-7.
- ALS - Tohgi H, Abe T, Yamazaki K, Murata T, Ishizake E,
Isobe C. Increase
in Oxidized Products and Reduction in Oxidized Glutathione in
Cerborospinal
Fluid From Patients with Sporadic Form of Amyotrophic Lateral
Sclerosis.
Neurosci Lett. 1999 Feb 5; 260(3):204-6.
6) Toxicology
- Detoxifies certain drug overdoses - Acetaminophen has been shown to reduce
glutathione production, thus paving the way for enhanced brain
destruction
by metabolic acids. (Perlmutter D. July 2004, 5th ed:108)
- Detoxifies substances in cigarette smoke and auto exhaust -
Rahman I,
MacNee W.
Lung Glutathione and Oxidative Stress:
Implications In Cigarette Smoke-Induced Airway Disease. Am J
Physiol. 277(6
Pt 1);1067-88,
1999 Dec.
- Detoxifies pollutants including heavy metals and pesticides -
Elevated
glutathione levels have been shown to protect tissue form lipid
peroxidation
created by exposure to certain metals. Consider infusions of
glutathione to
relieve the body burden of both neurotoxins and metal toxicity,
including
mercury. (Foster, JS.
Kane PC, Speight N. The Detoxx Book. 2002;90) - Prevents hearing loss from noise pollution
- Detoxifies many well-known carcinogens
7) Immunology
- Anti-viral for AIDS, hepatitis, herpes, etc. -
Low glutathione levels in
HIV clients may contribute to their immune deficiency since
glutathione
plays an important role in the function of lymphocytes. Some
lymphocytes
require adequate levels of glutathione in order to function
normally, and
HIV induces oxidative stress that depletes the cells of glutathione.
Townsend DM, Tew KD, Tapero H.
The Importance of Glutathione in Human
Disease. Biomed Pharmacother. 2003
May-June;57(3-4):145-55. Droge W, Holm E.
Role of Cysteine and Glutathione in HIV
Infection and other Diseases Associated with Muscle Wasting and
Immunological Dysfunction.
FASEB J, 11(13):1077-89 1997 Nov.
- Lyme Dis-Ease - Lyme dis-ease is a seriously complex
multi-system acidic
inflammatory condition that is triggered by bacterial exotoxins.
Glutathione helps to remove exotoxic and/or mycotoxic acids by
forming a
soluble compound with them, which can then be excreted through the
urine or
gut. (Can Glutathione Help Lyme Disease Suffers? Excerpt from: The
Glutathione
Report: Opitmal Health with the Master Antioxidant, Issue 4, Volume
1, May
2004).
- Natural antibiotic
- Chronic fatigue syndrome - An article in the journal of
Medical Hypothesis
proposed that glutathione, an anitoxidant essential for
lymphocyte function,
may be depleted in Chronic Fatigue Syndrome patients.
Glutathione is needed
for both the immune system and for aerobic muscular contraction.
The
authors proposed that glutathione depletion by an activated immune
system
also causes the muscular fatigue and myalgia associated with Chronic
Fatigue
Syndrome (Bounous et al. 1999).
8) Metabolic
- Athletic enhancement
- Decreases recovery time from physical stress
- Supports hemoglobin in kidney failure
- Diabetes - The blood and tissues of diabetics are marked
by critically
low glutathione levels. Glutathione depletion may have adverse
consequences in diabetic clients independent of glycemic control,
and it may
weaken the defense against oxidative stress. De Mattia G, Bravi MC,
Laurenti
O, Cassone-Faldetta M, Armiento A, Ferri C, Falsano F. Influence of
Reduced
Glutathione Infusion on Glucose Metabolism in Patients with
Non-insulin
Dependent Diabetes Mellitus. Metabolism.
1998 Aug;47(8):433-8.
Glutathione provides the body with tools to fight off these threats
naturally. Healthy people also benefit from elevated glutathione
levels
through an enhanced ability to fight off acidic toxins, dis-ease,
pre-cancerous cells and the aging process itself. Diminished
glutathione
levels are a symptom of aging and are particularly evident in such
aliments
as Parkinson's dis-ease and Alzheimer's dis-ease.
Glutathione is also important to physically active people.Many
world-class
athletes are discovering that well-maintained glutathione levels
gives them
the edge over their competitors, bringing greater strength and
endurance,
decreased recovery time from injury, less muscle pain and fatigue,
and
muscle-promoting activity.
Putting It All
Together
1) Medical science is still ascertaining all the critical roles
played by
glutathione in dis-ease resistance and general good health.
Clinical
evidence links low glutathione levels to the most common illnesses
of our
time as well as newly emerging dis-eases.
2) As an essential aid to health, glutathione works as the master
antioxidant in our body, optimizes the white blood cells and
detoxifies a
long list of pollutants and carcinogens or acids. The best way to
raise
glutathione levels is by eating foods that are high in glutathione
such as
avocados.
3) Pharmaceutical medicine has created drugs that do this very
effectively.
They have their uses in critical situations. But they also have
side
effects and repeated use is clearly inadvisable.
_________________________________________________________
References: Aging
It is well known that aging is accompanied by a precipitous fall in
gluathione levels. Lower glutathione levels are implicated in many
dis-eases associated with aging including cataracts, Alzheimer's,
Parkinson's atherosclerosis and others.
Journal of Clinical Epidemiology 47:1021-26, 1994.
Antioxidant Functions
Antioxidants are well documented and known to play vital roles in
health
maintenance and dis-ease prevention. Glutathione is your cell's own
major
antioxidant. Maintaining elevated glutathione levels aids the
body's
natural antioxidant function.
Biochemical Pahrmacology 47: 2114-2123, 1994.
Neurological Dis-Ease
Low glutathione levels have been associated with nuero-degenerative
dis-eases such as MS (Multiple Sclerosis), ALS (Lou Gehrig's Dis-ease),
Alzheimer's and Parkinson's. The Lancet 344: 796-798, 1994. Cancer
Glutathione plays a role in eliminating many carcinogens/acids and
also
maintains and optimizes white blood cell function while providing
stronger
anti-acidic/anti-tumor defenses.
Cancer Letters 57: 91-94, 1991.
Athletic Performance
Raised glutathione levels help increase strength and endurance.
Those
interested in physical fitness can benefit from a definite athletic
edge. Journal of Applied Physiology 87: 1381-1385, 1999. Toxins, Pollution and Radiation
Glutathione detoxifies a variety of pollutants, carcinogens and
poisons
including many found in fuel exhaust and cigarette smoke. It also
retards
damage from radiation exposure due to the eroding ozone layer.
Annual Reviews of Biochemistry 52: 711-760, 1983
AIDS
Glutathione levels correspond to poor survival of AIDS patients.
Much
documentation demonstrates the role of enhanced glutathione levels
in AIDS.
Proceedings of the National Academy of Science, USA 94: 1967-72,
1997.
Heart Dis-Ease, Stroke and Cholesterol
Raised glutathione levels fight the oxdiation of fats circulating in
the
bloodstream including cholesterol, retarding the process of plaque
formation
in the arteries leading to most heart attacks and strokes.
Nutrition Reviews 54: 1-30, 1996.
Diabetes
Diabetics are more prone to 'out-fections' and circulatory problems
leading
to heart dis-ease, kidney failure and blindness. Glutathione
protects
against the complications of diabetes.
Clinical Science 91:575-582, 1996
Lung Disease
Doctors have used glutathione-promoting drugs to treat many lung
diseases
including asthma, chronic bronchitis and emphasema. New and
potentially
therapeutic roles can be found for cigarette smoke damage, pulmonary
fibrosis and other illnesses.
American Journal of Medical Science 307:119-127,
1994
Digestive Disorders
Glutathione protects the body from inflammation of gastritis,
stomach
ulcers, pancreatitis and inflammatory bowel dis-ease including
ulcerative
colitis and Crohn's dis-ease.
Gut 42: 485-492, 1998
Hepatitis
The liver is a major storehouse for glutathione.
Glutathione is impaired in alcohol hepatitis as well as in viral
(acidic)
hepatitis including hepatitis A, B, and C. Raisied glutathione
levels help
restore liver function.
Americal Journal of gastroenterology 91: 2569-2573, 1996 Kidney Dis-Ease
Those with kidney failure or on dialysis suffer from high levels of
oxidative (acidic) stress and decreased glutathione levels.
Raised
glutathione levels help prevent anemia.
Nephron 61: 404-408, 1992
Pregnancy, Lactation and Childbirth
Glutathione's role in fetal and placental develoment is critical.
It also
acts in the placenta to detoxify pollutants before they can reach
the
developing child. Many complications of pregnancy have been linked
with
poor glutathione levels.
Autism is a mysterious and devastating disorder that is believed
to affect as many as 500,000 children in this country.
No one knows for certain what causes autism, but one theory —
chelation— has sparked controversy. Now, Jim Adams wants to put that
theory to the test. In a desperate quest for answers, he is using
his scientific know-how to test a controversial therapy called "chelation."
And he has a special reason for taking on this mission — his
daughter Kim. This report aired Dateline Sunday, June 4, 7 p.m.
To see part 1 of this report:
To see part 2 of this report:
Parents are able to prove vaccination caused autism in their
children.
LifeWave Carnosine and Glutathione booster patches are a more
effective delivery system because it is natural and self regulating.
Carnosine and Glutathione are the master antioxidants in the body
LifeWave Glutathione and Carosine booster patches act like little
antennas...programming the body to produce more of these naturally
occurring amino acids found in the human body.
They are effective simply by PLACING over the
meridian of the body they were designed for. Parents reported
benefits in their children after as few as 2 weeks, in the areas of
socialization, expressive language, alertness level, energy level,
adaptation to change, and curiously, gross motor planning.
Glutathione levels have reached 700 on several people using these
patches after several months time...The patches have a calming
benefit for Autistic Spectrum Disorder children .. do better in
school in the areas of socialization, expressive language, alertness
level, energy level, adaptation to change, and curiously, gross
motor planning while wearing these patches.
The use of the LifeWave Carnosine and Glutathione booster patches
can initiate detoxification symptoms very rapidly with high risk
individuals (heavy smokers, people exposed to occupational chemicals
and toxins like hair dressers, dentists, welders, crop dusters,
roofers, painters, etc). It is important to recognize that this is a
natural outcome from any approach that increases levels of the
antioxidant glutathione.
Dr. Haley believes that "stimulating glutathione production
inside the cells is THE most important factor when it comes to
effective treatments for autism."
In the July, 2007, Back to Basics column we covered the
devastating effects of mercury poisoning and the fact that many
Americans experience the effects of mercury being slowly released on
a daily basis from dental fillings. Due to this fact, the most
important step to take in removing mercury from your body is to
safely remove the mercury amalgams.
Simply removing them is NOT a safe method. There is actually a
science to this process. Dozens of dentists throughout the country
have dedicated themselves to learning exactly how to do this safely
and with the least amount of adverse effects.
This is undoubtedly the most expensive part of detoxing from
mercury—removing the source that is in your mouth. An estimated 85
percent of Americans have at least one mercury filling (each filling
being approximately 50 percent mercury) and most have several
mercury amalgams. The constant off-gassing of mercury suppresses
normal immune function by up to 88 percent when compared to a
non-mercury burdened body.
The presence of mercury, aluminum and other heavy metals such as
cadmium and lead can cause a virtual breeding ground for yeast,
fungi, parasites and pathogens in our digestive tracts. Many common
health problems today, as mentioned in last month’s column, can be
resolved by removing these metals and going on a yeast elimination
diet.
To check for the presence of heavy metals, many people still go
by hair analysis. However, most experts on heavy metal poisoning
have determined that a urine analysis is more accurate since urinary
porphyrins reveal the presence of mercury and other toxic metals by
evaluating the porphyrin pathway.
Some people may be thinking that, since they do not have any
mercury amalgams, this information does not apply to them. Wrong!
Our food, air and water are constant sources of heavy metals. The
ability of our liver to detoxify from the increasing amounts of
metals we are exposed to depends directly on the nutrient content of
our diets.
Chemistry professor Dr. Boyd Haley is an expert on mercury
toxicity and wrote an article, "Concepts for Safe Human Body Mercury
Removal." In this paper Dr. Haley stresses the importance of first
utilizing natural vitamins and supplements instead of automatically
using such chelating drugs as EDTA, DMSA or DMPS.
The most important supplements that will assist in your body’s
ability to excrete mercury and other heavy metals are ascorbates
(vitamin C), lipoic acid, methylcobalamin (Methyl B-12), B-6,
magnesium, selenium, melatonin, methionine, and glutathione.
Dr. Haley also believes that stimulating glutathione production
inside the cells is THE most important factor when it comes to
effective treatments for autism. Mineral supplements such as Zeolite
are also very helpful since our bodies tend to store heavy metals
when there is a deficiency in bio-available minerals.
Dr. Armand DeFelice, a Spokane, Washington dentist, specializes
in safely removing mercury amalgams, He claims that he can detoxify
a patient from mercury poisoning in six months using a protocol he
developed using supplements from Standard Process Labs.
Glutathione (GSH): After hearing many
testimonials and reading several articles, it is clear that having a
deficiency of glutathione is a precursor for one’s inability to
effectively excrete mercury, aluminum, and pesticides from the body.
GSH is an antioxidant, immune booster and detoxifier. Without it,
your cells would disintegrate from unrestrained oxidation, your body
would have little resistance to bacteria, viruses and cancer and
your liver would literally shrivel up from eventual accumulation of
toxins.
The research being done on glutathione is enormous with over
77,280 papers available at PubMed.com that mention GSH. Healthy
cells homeostatically oppose free radicals through the use of
antioxidants, of which GSH plays a significant role. GSH is the most
powerful antioxidant occurring naturally in the cells of our body.
The effectiveness of other antioxidants like vitamins C and E
depends on the availability of GSH. This is also why GSH is
essential in overcoming and preventing cancer, auto-immune diseases
and other immune system related disorders.
GSH plays a key role in detoxification, having the ability to
bind to heavy metals and other toxins through its sulfur molecules,
thereby providing the means for the body to eliminate these toxins.
Studies have shown that children with autism have low levels of GSH
which researchers attribute to abnormalities in their methionine
pathway. Another extremely important function of GSH is its ability
to protect (or at least minimize) the deadly effects on our cells
from all forms of radiation, from x-rays to microwaves.
The following is from Dr. Deborah Baker’s website:www.y2khealthanddetox.com:
"A recent research article published in the journal Radiology
states that ‘radiation from a single whole-body scan is equal to
that from 100 mammograms and is similar to that received by
survivors of the atomic bombings of Hiroshima and Nagasaki,
Japan—about 1 mile from the explosions—according to radiation
biologist, David J. Brenner of Columbia University. The radiation
from one scan is enough to produce a tumor in one out of 1,200
people and, for those who have annual scans, the risk increases to
one tumor in every 50 people.’ With inadequate intracellular GSH the
risk is greatly increased."
Dietary sources of GSH: Glutathione is
synthesized from three amino acids - cystein, glutamate and glycine.
Since most healthy diets rich in raw fruits and vegetables have an
abundance of glutamate and glycine, the focus should be on dietary
sources of cystein. Cystein content is relatively high in proteins
found in eggs, meat, red peppers, garlic, onions, brussel sprouts,
oats, milk, whey protein, and wheat germ. Fruits and vegetables that
are high in these precursors to GSH production are avocado,
watermelon, asparagus, grapefruit, potato, acorn squash,
strawberries, orange, tomato, cantaloupe, broccoli, okra, peach,
zucchini, and spinach.
Dr. Baker claims that avocado, asparagus and walnuts are
particularly good sources. Cystein is also metabolized by the body
in the presence of methionine, these two amino acids being the two
sulfur-containing amino acids. She also warns that, due to the
stress our bodies are under dealing with the myriad of pollutants in
today’s world, it is important to supplement. Dr. Baker claims that
the only effective GSH supplementation that reaches the inside of
our cells is a product called GSH complex which she sells for $64 -
10.5 oz. Others have gotten good results using N-acetyl-L-cysteine
(NAC) which increases vital cellular glutathione levels. NAC
powerfully neutralizes mercury as a poison if 500 to 750 mg. are
taken daily. Other helpful treatments for better metabolism of GSH
include Epsom salt baths and MSM supplementation.
Herbs for eliminating metals: There are several herbs that are
useful in the elimination of heavy metals. Tenna Merchent wrote her
odyssey of detoxing herself and her son from aluminum poisoning in
her highly readable book, "He’s not Autistic But...How We Pulled
Our Son From the Mouth of the Abyss." Merchant claims that one
should use pure vegetable glycerine to eliminate mercury;
bladderwrack, a seaweed, for aluminum; potassium for excess copper;
and horsetail (shavegrass) for lead.
Others have found that cilantro and chlorella are helpful for
mercury elimination with many advocates making a delicious pesto
using cilantro that includes lots of raw garlic.
Again, bio-available minerals are important and many herbs are
excellent sources of these important nutrients. Dr. John R.
Christopher has a formula that has been specifically designed for
eliminating these heavy metals from the body. His "Heavy Mineral
Herbal" formula contains bugleweed, cilantro, yellowdock and
lobelia.
Another herb that is gaining popularity is turmeric, which
contains curcumin. Using this "spice" in therapeutic doses has shown
promise in treating Alzheimer’s patients, who are known to be loaded
with both mercury and aluminum.
Liver Health: When on any detoxification
program, it is essential to make sure your liver is also cleansed
and protected. [See Back to Basics for March and April, 2007.] Milk
Thistle is extremely important as are other blood purifying and
liver cleansing herbs. We find taheebo (pau d’arco), barberry,
dandelion root, chaparral, and red clover to be absolutely essential
supports in the liver detoxification process.
EDTA, DMSA and DMPS: These are the most common
ways of chelating mercury from the body. While these chelating
treatments are available in both oral and IV forms, it is well
recognized that DMPS has the track record for the being the fastest
way to remove mercury and lead from the body—and is the longest
lasting. Many people have found these treatments harsh on their
bodies, having a tendency to also chelate beneficial minerals.
Not everyone has success with this method as Dr. Rashid Battar
found when treating his autistic son. As a result he developed a
transdermal DMPS designed specifically for chelating mercury in
autistic children. However, this method does require a prescription.
Clay baths: Many people have used magnetic clay
baths successfully in detoxing from mercury, aluminum, radiation and
other environmental pollutants such as those found in "chemtrails."
The results people experience using this method are phenomenal
and definitely worth the money when it comes to actually getting
metals and other chemicals out of your body. It takes a few baths
to have the full effect but after the first successful bath, you
will likely be "hooked" and want to share this method with others.
Twelve specific clay baths, each bath enhanced with herbs designed
to pull out the particular contaminant(s) needing removal, are
available at
www.magneticclay.com
Ionic Foot baths and Foot pads: This is a fairly
innovative way of pulling out heavy metals and other toxins through
the feet. Many practitioners who use the foot baths in their offices
recommend drinking a lot of water afterwards followed by ionic
mineral supplementation. There are certainly a "boat load" of
fabulous testimonies with these baths, though lab analysis of the
water after treatments is rare. The foot pad method works on the
same principle of pulling out metals/toxins through the feet; this
method being fairly effortless since one applies the pads to the
soles of their feet when they go to bed at night. The testimonial at
www.bodypurenow.com is by a
dentist who claims the following toxins came out of his body
through his feet—mercury, isopropyl alcohol, benzene, nickel,
asbestos, dimethylaminoazobenzene and PCBs. This same website offers
a free analysis of the toxins in used foot pads that are purchased
from them.
The Cancer Connection: According to a new book
by Italian oncologist Tulio Simoncini, M.D., "Cancer is a Fungus,"
overgrowth of candida albicans (yeast/fungus) is at the root
of all cancers. Since accumulation of both mercury and aluminum in
our bodies lays the perfect foundation for the overgrowth of candida,
this doctor’s book is proof of what many holistic practitioners have
known for years. Simoncini also points out that "chemotherapy favors
the fungus...and is a leading cause of metastasis."
Energetic Healing: Wave of the Future: The most
exciting, "inexpensive" and simple way to release heavy metals from
your body is described in Tenna Merchent’s book mentioned earlier.
She describes how she went to a master herbalist who released the
aluminum toxicity in her body and that of her son’s through a simple
prayer: "Jesus, I ask that You release the reverse polarity in
___’s brain, body and energy field. I ask that You reabsorb his
healthy polarity back into his body as God intended it, and I ask
that You restore his body to a state of unconditional love and
forgiveness as God intended it."
The key three steps in this prayer are Release, Reabsorb, and
Restore. After this prayer was "broadcast," the aluminum toxicity in
Tenna and her son was cleared and they became "allergy-free."
For many people this simple method will test your faith in the
power of God to work through you for healing. One woman found that
it took 50 repetitions to get clear on her intention and faith in
this method. Tenna also utilizes a pendulum for both diagnosis and
sorting through particular herbs and other remedies for her family.
She also utilizes "release codes" which one person describes this
way: "Each letter and number has its own geometry and vibration.
This geometric vibration can be imprinted onto a person through a
release code in a way similar to how one of the homeopathic machines
imprints a homeopathic vibration onto a remedy."
She uses as an example a release code for a woman with
infertility issues, the code being 2GK7M4324, noting that each code
is individual for that particular person’s energetic issues related
to the health problem.
The future: The wave of the future is in
vibrational healing and empowering families to take charge of their
own healthcare needs. This is the primary reason I decided to end
this column with a few gems gleaned from Tenna Merchent’s
inspirational book, "He’s Not Autistic But... How We Pulled Our Son
From the Mouth of the Abyss." This book details her very personal
story of trials and tribulations as she explored every avenue
possible to heal herself and her son from aluminum toxicity and, in
the process, became her family’s "healer."
He’s Not Autistic But....How We Pulled Our Son From the Mouth
of the Abyss by Tenna Merchent is now available from Vaccination
Liberation for $20 (includes S&H). Mail check or M.O. to:
Vaccination Liberation, P.O. Box 457 Spirit Lake, Idaho 83869.
Studies show that sixteen out of eighteen children with autism have
extremely high levels of heavy metal toxins in their bodies. These
levels were higher than adult levels that are considered to be
extreme. One may wonder how these children were exposed to such high
levels of these toxins or if their mothers were greatly exposed when
pregnant. However, Autistic children do not have the normal ability
to eliminate these toxins from their body as others do. As a result
there is an extreme build up.
Heavy metal build up can cause
behavioral problems, cognitive issues, as well as physiological
problems. Some toxins, which affect a person in these areas, are
Mercury, Aluminum, Arsenic, Copper, and Lead.
When someone has aluminum toxic material build up in their body
they may experience, depression, blurred vision, numb hands and
feet, headaches, and even abnormal heart beat. In addition a person
may have issues when it comes to both recall and long-term memory.
Mild symptoms of arsenic toxicity include vomiting, muscle
cramps, anorexia, pain in the stomach, diarrhea, a burning sensation
in the throat and mouth, fatigue and overall feeling of illness.
Some possible symptoms of copper toxicity, are vomiting,
headaches, vertigo, fever and chills, diarrhea, and even a taste of
metal in the mouth.
We hear much about lead poisoning and this is one of the worst
toxic build-ups one can have in the body. One may have problems with
their memory, trouble concentrating, and motor skill impairment.
However, in the worst cases one can experience, damage to the
central nervous system, brain damage, seizures, and even death.
Even though children with autism may not have levels toxic levels
of these substances to this degree, a build up of these toxins can
play a role in the condition.
Can a natural mineral help children with Autism? Studies say yes.
This mineral is Zeolite and it has been approved by the BioMed IRB
of California to be added to the treatment of children who suffer
from Autism.
Since it is believed that heavy metals may be a cause of Autism
in children. Zeolite removes heavy metals and toxins form the body.
Zeolite is a negatively charged mineral which posses a honeycomb
like structure, which cannot be seen under microscope. These
structures have been proven to have the ability to attract toxins
and heavy metals thus trapping them. After these metals are trapped
they are removed from the body.
It has been noted that children who have made great recoveries
from their Autism took part in some form of metal detoxification
treatments. If you wish to have the levels of heavy metal build up
tested in your child, you may do so with a simple hair test.
A person's hair has the ability to retain toxic elements, which
are present in your body among other things; this is why many
companies are now performing drug tests by taking samples of hair
from their employee's head. Drugs use from as far back as a year
will be revealed through the hair.
If you wish to find out if your child has built up toxins in
their body, there are test available that will measure the level of
toxic elements, which are present. In addition talk to your doctor
about heavy metal detoxification products.
There is a potential breakthrough in the treatment of autism coming
from the Chicago area.
Eight-year-old Jonathan Sieger is autistic. Jane McDonald, 6, has
developmental disorders. Drugs and therapies help their conditions, but
they are both showing even more improvement recently by taking a
supplement found in health food stores.
I was shocked that we saw so much improvement early on after using
it, said Janes mother, Diane Curtis. Jonathans mother expressed similar
satisfaction with her sons improvement. Hes just so much happier. That
was our first immediate notice, Maureen Sieger said. Jonathan and Jane
have been taking a synthetic version of a natural protein called l-carnosine.
Their pediatric neurologist, Dr. Michael Chez of Lake Bluff, Ill., has
recently completed the first study of the substance. It affected
language, receptive language, eye contact, communication, all of which
are things which children with autism have big gaps with, Chez said.
Over an eight-week period, Chezs study showed that carnosine improved
behavior and communication by 16 percent. Social interaction improved by
27 percent and, in just four weeks, parents reported an overall
improvement that more than doubled through the length of the study. More
and more research shows that the frontal lobes and the temporal lobes in
the brain control emotion, epileptic activity, cognitive, expressive
speech, and abstract thinking. Chez said I-carnosine apparently works in
the front part of the brain. So far, he said hes used it on about 1,000
children, with a 90 percent success rate. According to Dr. Chez,
children in his study improved in receptive language, auditory
processing, socialization, awareness of surroundings, fine motor
planning and expressive language. Responses to supplementation were seen
1 to 8 weeks into supplementation.
On some children, the change has been dramatic. He runs into gym
class. He wants to play tag. He wants to play with the other children
and hes really happy to be at school for the first time, Maureen Sieger
said.
For autistic children, Doctor Chez finds most beneficial a dosage of
400 mg carnosine in combination with 50-IU Vitamin E and 5 mg zinc twice
a day. The zinc and Vitamin E are included because Dr. Chez believes
that the addition of small doses of zinc may augment intracellular
L-Carnosine activation, and vitamin E may enhance antioxidant
neuro-protective properties of L-Carnosine. In some children, too high a
dose may overstimulate some patients frontal lobes which can cause
increased irritability, hyperactivity or insomnia which was observed
already in hyperactive autistic children. Other than that, there were no
side effects. Children with other disorders such as epilepsy, central
processing disorder, or brain injury dosages from 200 to 3000 mg per day
based upon Dr. Chezs evaluation.
More studies will be needed to confirm the results of Chezs
study.
A summary of Dr. Chez study is as follows:
Double-Blind, placebo-controlled Study of L-carnosine supplementation
in children with autistic spectrum disorder
Michael G. Chez, M.D., Cathleen P. Buchanan, Ph.D.,
Jamie L. Komen, M.A., Marina Becker, R.N.
Objective: L-Carnosine is an amino acid dipeptide that may enhance
frontal lobe function. We therefore sought to investigate whether L-Carnosine
supplementation for children with Autistic Spectrum Disorders (ASD)
results in observable, objective changes in language and/or behavior in
contrast to placebo.
Design/Methods: Thirty-one children (21 M, mean age=
7.45; range = 3.2-12.5 yrs )meeting inclusion criteria were enrolled in
an 8 week blinded trial of either 400 mg BID powdered L-Carnosine or
placebo. Children were assessed at a pediatric neurology clinic with the
Childhood Autism Rating Scale (CARS), the Gilliam Autism Rating Scale
(GARS), the Expressive and Receptive One-Word Picture Vocabulary tests
(E/ROWPVT), and biweekly parental Clinical Global Impression of Change
(CGI), at baseline and 8 week endpoint.
Results: Children who were on placebo (n=17) did not
show statistically significant changes on any of the outcome measures.
After 8 weeks on L-Carnosine, children (n=14) showed statistically
significant improvements on the GARS total score, GARS Behavior,
Socialization, and Communication subscales, and the ROWPVT (all p’s<.05).
EOWPVT and CARS showed trends in improvements, which were supported by
parental CGI.
Conclusions: Oral supplementation with L-Carnosine
resulted in demonstrable improvements in autistic behaviors as well as
increases in language comprehension that reached statistical
significance. Although the mechanism of action of the amino acid is not
well understood, it is believed that it acts to modulate
neurotransmission and affect metal ion transfer of zinc and copper in
the entorhinal cortex. This may enhance neurological function or act in
a neuroprotective fashion.
Carnosine is a naturally occurring nutrient in our bodies whose
production declines with age. Clinical research on Carnosine has
produced some amazing and dramatic results including the knowledge that
Carnosine may be the principle nutrient for keeping the body healthy. In
fact, numerous people that have used our Carnosine Booster have reported
remarkable improvements in wellness and physical performance even within
a few days of use.
These results have never been available before LifeWave.
Our Carnosine boosting patch is much more powerful than any other method
of elevating Carnosine levels.
FACTS about Carnosine:
Carnosine is a material that is found naturally in the human
body
As we age our bodies levels of Carnosine start to decline,
necessitating the need for supplementation
Carnosine is an antioxidant and plays an important role in our
overall health
Studies on Carnosine show that it can protect the brain from
plaque, one of the causes of Alzeimers disease.
Studies on Carnosine show that it protects our DNA better than
any other nutrient
Carnosine has the unique ability to turn old cells into young
and healthy cells!
Carnosine is known to accelerate wound healing through repair of
connective tissue
Patents have been issued for using Carnosine to improve athletic
performance; this is possible because Carnosine helps to prevent the
build up of lactic acid in our muscles
There are other Carnosine supplements on the market, but clinical
research shows that common Carnosine pills, powders and drinks can only
elevate blood Carnosine levels by trivial amounts in 30 days.
Because LifeWave technology is capable of triggering metabolic
changes within the cells, our Carnosine Booster goes to work right away
and is effective even within the first 24 hours of use!
They are effective simply by PLACING over the meridian of the body
they were designed for. Parents reported benefits in their children
after as few as 2 weeks, in the areas of socialization, expressive
language, alertness level, energy level, adaptation to change, and
curiously, gross motor planning.
Glutathione levels have reached 700 on several people using these
patches after several months time...The patches have a calming benefit
for Autistic Spectrum Disorder children .. do better in school in the
areas of socialization, expressive language, alertness level, energy
level, adaptation to change, and curiously, gross motor planning while
wearing these patches.
The Lifewave Carnosine booster patch has such promise for helping
Autism and other Autistic Spectrum Disorders conditions as it is a more
effective delivery system then the pills cited in the studies below...
Dr. Michael Chez Study
What is Carnosine?
The supplement that you are interested in learning more about
contains 200mg powdered carnosine, as well as powdered Vitamin E (25IU)
and powdered Zinc (2.5 mg). The exact dosage that is correct for your
child should be established by your doctor in coordination with Dr.
Michael Chez, who pioneered the use of this supplement in children with
developmental delays. L-carnosine, or "carnosine" is an amino acid
dipeptide made up of histidine and alanine. The naturally-occurring
amino acid is found within the human body, a by-product of proteins
digested within the body. The deep frontal part of the brain (entorhinal
cortex) is believed to be a site where carnosine tends to accumulate. It
may interact with zinc in that area, as well as having effects on GABA,
a brain neurotransmitter, which by a complex chemical reaction forms
homo-carnosine.
What Studies Have Been Done with Carnosine?
Rat and animal studies have been done with carnosine looking at
"neuroprotection." These investigations aimed to examine protective
function. There have been no studies that have shown any evidence of
toxicity or teratogenicity in animals where carnosine has been studied.
Few scientifically-validated human studies have been conducted, however,
and most of the information one finds about carnosine's claims are of
the quality found on the intenet. Claims have been made for generic
carnosine/carnosine formulations aiding in combatting a range of
maladies from Alzheimer's to body building.
Recent MRI studies by Petroff and colleagues (2001) examining levels
of brain chemistry showed a relationship between homo-carnosine and GABA
in temporal lobe and generalized myoclonic epilepsies. These authors
described homo-carnosine levels that may correlate with seizure control
even when GABA response is defective in human studies. Dr. Chez was
intrigued by the results of this study, and thus began a study in June,
2001 that aimed to test if supplementing carnosine orally could enhance
seizure protection in children who were already on anticonvulsants and
who had recurrent seizures despite being on standard drug therapy. He
hypothesized that the addition of carnosine could decrease seizure
frequency and so began an open-label study of carnosine which he
acquired via an industrial chemical company.
The Open-Label Study
A total of 75 children, who had "failed" multiple
antiepilepticmedications in an effort to stop their seizures (including
steroids and the Ketogenic diet) with histories of partial or
generalized epilepsy entered the open-label study. The majority
fronto-temporal lobe seizures, or generalized epilepsy. Approximately
25% had EEGs to directly compare before and after starting the
carnosine. Many patients had reductions in seizure frequency, but
without EEG correlation. Two sisters with hypsarrythmia/Lennox-Gastaut
variant both showed dramatic improvements in EEG amplitude, spike
frequency, and background activity. In three other patients with primary
or secondary generalized spike and wave patterns or Lennox-Gastaut type
patterns, EEG amplitude and spike frequency improved with carnosine in
dosages of 800-2,000 mg. per day. Dosage was titrated upward depending
upon bodyweight. No side effects were reported. Unexpectedly, parental
diaries showed a pattern of comments related to gains in cognitive
domains including language, alertness, energy levels, and even gross
motor ability. Dr. Chez was motivated by such reports in addition to
comments from other professionals that worked simultaneously with the
children (e.g., speech therapists) who, unaware that children were on
the new supplement, spontaneously stated that individual children were
showing incremental gains not previously seen. Expressive language was
described as more fluent, eye contact more frequent, and interest in the
environment was more prominent. Dr. Chez thought that this supplement
could be of benefit to children with autism or PDD and so began to give
it to children with such diagnoses in an open-label trial.
Indeed, parents reported benefits in their children after as few as
2 weeks, in the areas of socialization, expressive language, alertness
level, energy level, adaptation to change, and curiously, gross motor
planning.
The Double-Blind Study
Because of the remarkable cognitive improvements in language, speech
production and school performance as well as social alertness, Dr. Chez
felt it important to study the effect of the supplement in children with
Autistic Spectrum Disorders. Children were included in this study if
they had histories of abnormal EEG, and had previously responded to
cognitive-enhancing dementia medications (as part of a controlled study
at the office) or to anti-convulsants. A double-blind placebo controlled
study with carnosine was begun. Children were randomly placed on either
active carnosine or placebo. Expressive and receptive language measures,
two autism rating scales, and parent rating analog scales were
administered at the start and completion of the study. Results of this
study indicated clinically meaningful changes in many aspects of
autistic features, and also showed that the carnosine supplement
improved children's expressive and receptive language significantly.
This is the only dietary supplement to date studied in a double-blind
fashion in autism.
Who Benefits and What are the Side Effects?
The majority of children with either epilepsy or autism treated in
open label studies by Dr. Chez benefitted from carnosine
supplementation. Dr. Chez estimates that approximately 10% of children
who have been on the carnosine supplement have had reports of no
improvement. A very small percentage (less than 5% of children with
epilepsy or autistic spectrum disorders) have shown increased physical
hyperactivity or verbal hyperactivity, but we are unable to ascertain if
these reports are directly related to the carnosine supplement. No sleep
disturbances were reported as a result of carnosine therapy even in
dosages up to 3,000 mg. a day. No abdominal side effects, skin rashes,
or any changes in anticonvulsant blood levels, liver functions or
hematological studies. No patients had any urinary changes or bowel
habit changes from the carnosine. Many children on the autistic spectrum
were reported to increase their range of food choices with an improved
range of appetite. Responses have been seen in generalized epilepsies,
focal seizure disorders, autism, PDD, and head injury to date. Because
of its effect on entorhinal cortex, improvements in Alzheimer's disease
or other frontal lobe encephalopathy may be possible. Any syndrome that
involves apraxia or expressive language delay may benefit from this.
Concurrent studies are currently being run or planned in areas of
attention disorder, Tourette's syndrome, and various learning disability
syndromes of the nonverbal type.
It has been proven that thimerosal (mercury in vaccinations
causes autistic spectrum disorder in children!
Detoxify your child with non-transdermal chelation.
Immunization Poll
New research linking immunizations to autism has reopened the
debate on whether or not immunizations have triggered autism in a
significant portion of the autistic community.
Thirmerosal Testimony
Thimerosal Testimony
CONGRESSIONAL TESTIMONY U.S. HOUSE OF
REPRESENTATIVES THE SUBCOMMITTEE ON HUMAN RIGHTS AND WELLNESS
COMMITTEE ON GOVERNMENT REFORM
SEPTEMBER 2004 HEARING
TRUTH REVEALED: NEW SCIENTIFIC DISCOVERIES REGARDING
MERCURY IN MEDICINE AND AUTISM
submitted by:
Mady Hornig, MD Director of Translational Research and
Jerome L. and Dawn Greene Infectious Disease Laboratory,
Associate Professor of Epidemiology Mailman School of Public Health
Columbia University
Chairman Burton, Congressman Watson, and Members of the
Subcommittee, Thank you for the opportunity to submit for the record
this statement regarding our new animal model of the toxicity of
thimerosal (ethylmercury preservative in vaccines) and its
implications for human health. I regret that I am unable to
personally present this testimony today due to a family medical
emergency. Our work addresses whether genes are important in
determining if mercury exposures akin to those in childhood
immunizations can disrupt brain development and function. I also
submit for the record an electronic copy of the first paper
published on this animal model in the Nature Publishing Group
journal, Molecular Psychiatry (Hornig M, Chian D, Lipkin WI.
Neurotoxic effects of postnatal thimerosal are mouse strain
dependent. Mol Psychiatry 2004 9:833-845).
The premise of our research is that if mercury in vaccines
creates risk for neurodevelopmental disorders such as autism,
genetic differences are likely to contribute to that risk. We built
upon an extensive, existing literature on toxicity of other forms of
mercury in inbred mouse strains that affirmed the importance of
specific genes controlling immune responses (major
histocompatibility complex, or MHC) in determining mercury-induced
autoimmune outcomes in mice. Earlier studies, however, did not use
the form of mercury present in vaccines, known as thimerosal, and
did not consider whether during early postnatal development, when
the brain and immune systems are still maturing, might intensify
toxicity. Based on reports of immune disturbances and family history
of autoimmune disease in a subset of children with autism,
we hypothesized that immune response genes linked to mercury
immunotoxicity in mice would predict damage following low-dose,
vaccine-based mercury in our mouse model.
Our predictions were confirmed. Using thimerosal dosages and
timing that approximated the childhood immunization schedule, our
model of postnatal thimerosal neurotoxicity demonstrated that the
genes in mice that predict mercury-related immunotoxicity also
predicted neurodevelopmental damage. Features reminiscent of those
observed in autism occurred in the mice of the
genetically sensitive strain, including: generalized behavioral
impoverishment and abnormal reaction to novel environments;
enlargement of the hippocampus, a region of the brain involved in
learning and memory; correlation of hippocampal enlargement with
abnormalities in exploration and anxiety; increased packing density
of neurons in hippocampus; and disturbances in glutamate receptors
and transporters. Only mice carrying the H-2 s susceptibility gene
showed these autism - like effects (SJL/J mice). Two mouse strains
with different H-2 genes (C57BL6/J mice, H-2 b ; BALB/cJ mice, H-2 d
did not demonstrate adverse consequences following thimerosal
exposure.
It is important to emphasize that these animal model studies do
not provide conclusive evidence regarding a link between mercury
exposure and sm. Nonetheless, the finding that a specific genetic
constraint profoundly alters the brains and behavior of
thimerosal-exposed mice confirms the biological plausibility of
thimerosal neurotoxicity, provides critical guidance for the
interpretation of existing epidemiologic investigations into the
potential association of thimerosal with neurodevelopmental
disorders, and suggests important new avenues for future research.
Our work implies that if genetic factors are operative in mediating
a link between thimerosal and autism in humans,
then studies that fail to consider genetic susceptibility factors
will be compromised in their ability to detect a statistically
significant effect even if one exists.
Recent findings, presented at scientific meetings but as yet
unpublished, suggest that thimerosal neurotoxicity in susceptible
mice involves the generation of autoantibodies targeting brain
components. This autoimmune response persists long after the
presence of mercury can no longer be detected. If confirmed, these
findings will enable us to develop a human diagnostic test to
determine whether some individuals with autism have
similar autoantibodies present in their peripheral blood. Such work
would not only bring us a step closer to identifying the genes
associated with thimerosal neurotoxicity in humans, facilitating
prevention programs, it would also validate the utility of this
animal model for the development of safe and effective modes of
intervention.
It is highly likely that the neurotoxic effects of cumulative
mercury burden, including exposure to other sources or forms of
mercury (thimerosal in products other than vaccines; methylmercury
in contaminated fish), follow similar patterns of genetic
restriction; it is also likely that similar genetic factors
influence the neurotoxicity observed following exposure to
xenobiotics other than mercury (e.g., PCBs, the PBDEs used as flame
retardants in computers, and infectious agents). Age and
developmental status at the time of exposure, nutritional factors,
and gender are also known to influence outcomes. We have limited
ability to explain the interplay of such factors in humans; consider
the example of the disparate cognitive outcomes reported in children
in the Faroe Islands and the Seychelles after similar prenatal
methylmercury exposures. The reasons for this divergence remain
unclear. The design of future epidemiologic studies must take into
account the possibility of multiple xenobiotic exposures as well as
the influence of factors that modulate risk. Our studies have
important implications for understanding the role of
gene-environment interactions in the pathogenesis of autism
and related neurodevelopmental disorders.
I refer Subcommittee Members to our recent publication in
Molecular Psychiatry where experimental findings and their
implications are discussed in more detail.
Thank you for your attention.
Mady Hornig, MD New York, NY
Research on LifeWave Glutathione Patch
A double blind placebo controlled study was performed to
independently examine the effectiveness of the LifeWave Glutathione
patch in being able to elevate blood levels of Glutathione over a
period of 24 hours and several days.
Detoxify your child with
non-transdermal chelation.
disorders without needles, or drugs naturally!
A double blind placebo controlled study was performed to
independently examine the effectiveness of the LifeWave
Glutathione patch in being able to elevate blood levels of
Glutathione over a period of 24 hours and several days. Baseline
data was collected for all subjects; the average Blood
Glutathione levels for all individuals was an average of 2020
umole/L as displayed by the graph on the left ("Normal" value).
After 24 hours of using the LifeWave Skin Care/Glutathione
patch, the average blood Glutathione levels of all individuals
was 7326 umole/L.This means that within 24 hours of using the
LifeWave Skin Care/Glutathione patch the average increase in
Glutathione is over 3 TIMES HIGHER than normal. The graph on the
right shows how over a period of 24 hours blood Glutathione
levels increase dramatically for LifeWave patch users versus not
using the LifeWave Skin Care patch.
Blood Glutathione levels have been identified as being one of
the most important indicators of our overall health. As the
master antioxidant in the body Glutathione has a range of
diverse metabolic functions including acting as a free radical
scavenger, “recharging” depleted antioxidants back into their
active state (Vitamin C, Vitamin E, Vitamin A, etc.),
maintaining the immune system, supporting protein structures and
removing heavy metals such as mercury through the liver.
Present methods that attempt to elevate Glutathione levels
are not very effective. Oral supplements of Glutathione are
destroyed by stomach acids. Glutathione is a tri-peptide
composed of three amino acids and adding these amino acids to
the diet does not guarantee elevated levels of Glutathione.
Injections of Glutathione does translate into elevated levels of
Glutathione in the blood however this method is undesirable on a
daily basis, is expensive and inconvenient.
The LifeWave Glutathione patch is a new way to dramatically
increase Glutathione levels in the body on a daily basis. Our
clinical studies show that the AVERAGE increase in blood
Glutathione levels over a 24 hour period is a remarkable 3 TIMES
HIGHER than normal. Our patch technology makes elevating
Glutathione levels convenient, effective and safe.
Carnosine and Autism Study
There is a potential breakthrough in the treatment of autism
coming from the Chicago area.
Eight-year-old Jonathan Sieger is autistic. Jane McDonald, 6, has
developmental disorders. Drugs and therapies help their conditions,
but they are both showing even more improvement recently by taking a
supplement found in health food stores.
I was shocked that we saw so much improvement early on after
using it, said Janes mother, Diane Curtis. Jonathans mother
expressed similar satisfaction with her sons improvement. Hes just
so much happier. That was our first immediate notice, Maureen Sieger
said. Jonathan and Jane have been taking a synthetic version of a
natural protein called l-carnosine. Their pediatric neurologist, Dr.
Michael Chez of Lake Bluff, Ill., has recently completed the first
study of the substance. It affected language, receptive language,
eye contact, communication, all of which are things which children
with autism have big gaps with, Chez said.
Over an eight-week period, Chezs study showed that carnosine
improved behavior and communication by 16 percent. Social
interaction improved by 27 percent and, in just four weeks, parents
reported an overall improvement that more than doubled through the
length of the study. More and more research shows that the frontal
lobes and the temporal lobes in the brain control emotion, epileptic
activity, cognitive, expressive speech, and abstract thinking. Chez
said I-carnosine apparently works in the front part of the brain. So
far, he said hes used it on about 1,000 children, with a 90 percent
success rate. According to Dr. Chez, children in his study improved
in receptive language, auditory processing, socialization, awareness
of surroundings, fine motor planning and expressive language.
Responses to supplementation were seen 1 to 8 weeks into
supplementation.
On some children, the change has been dramatic. He runs into gym
class. He wants to play tag. He wants to play with the other
children and hes really happy to be at school for the first time,
Maureen Sieger said.
For autistic children, Doctor Chez finds most beneficial a dosage
of 400 mg carnosine in combination with 50-IU Vitamin E and 5 mg
zinc twice a day. The zinc and Vitamin E are included because Dr.
Chez believes that the addition of small doses of zinc may augment
intracellular L-Carnosine activation, and vitamin E may enhance
antioxidant neuro-protective properties of L-Carnosine. In some
children, too high a dose may overstimulate some patients frontal
lobes which can cause increased irritability, hyperactivity or
insomnia which was observed already in hyperactive autistic
children. Other than that, there were no side effects. Children with
other disorders such as epilepsy, central processing disorder, or
brain injury dosages from 200 to 3000 mg per day based upon Dr.
Chezs evaluation.
More studies will be needed to confirm the results of
Chezs study.
A summary of Dr. Chez study is as follows:
Double-Blind, placebo-controlled Study of L-carnosine
supplementation in children with autistic spectrum disorder
Michael G. Chez, M.D., Cathleen P. Buchanan, Ph.D.,
Jamie L. Komen, M.A., Marina Becker, R.N.
Objective: L-Carnosine is an amino acid dipeptide that may
enhance frontal lobe function. We therefore sought to investigate
whether L-Carnosine supplementation for children with Autistic
Spectrum Disorders (ASD) results in observable, objective changes in
language and/or behavior in contrast to placebo.
Design/Methods: Thirty-one children (21 M, mean
age= 7.45; range = 3.2-12.5 yrs )meeting inclusion criteria were
enrolled in an 8 week blinded trial of either 400 mg BID powdered
L-Carnosine or placebo. Children were assessed at a pediatric
neurology clinic with the Childhood Autism Rating Scale (CARS), the
Gilliam Autism Rating Scale (GARS), the Expressive and Receptive
One-Word Picture Vocabulary tests (E/ROWPVT), and biweekly parental
Clinical Global Impression of Change (CGI), at baseline and 8 week
endpoint.
Results: Children who were on placebo (n=17) did
not show statistically significant changes on any of the outcome
measures. After 8 weeks on L-Carnosine, children (n=14) showed
statistically significant improvements on the GARS total score, GARS
Behavior, Socialization, and Communication subscales, and the ROWPVT
(all p’s<.05). EOWPVT and CARS showed trends in improvements, which
were supported by parental CGI.
Conclusions: Oral supplementation with L-Carnosine
resulted in demonstrable improvements in autistic behaviors as well
as increases in language comprehension that reached statistical
significance. Although the mechanism of action of the amino acid is
not well understood, it is believed that it acts to modulate
neurotransmission and affect metal ion transfer of zinc and copper
in the entorhinal cortex. This may enhance neurological function or
act in a neuroprotective fashion.
Dr. Michael Chez, who pioneered the use of this supplement in
children with developmental delays. L-carnosine, or "carnosine" is
an amino acid dipeptide made up of histidine and alanine. The
naturally-occurring amino acid is found within the human body, a
by-product of proteins digested within the body. The deep frontal
part of the brain (entorhinal cortex) is believed to be a site where
carnosine tends to accumulate. It may interact with zinc in that
area, as well as having effects on GABA, a brain neurotransmitter,
which by a complex chemical reaction forms homo-carnosine.
The Open-Label Study: A total of 75 children,
who had "failed" multiple antiepilepticmedications in an effort to
stop their seizures (including steroids and the Ketogenic diet) with
histories of partial or generalized epilepsy entered the open-label
study. The majority fronto-temporal lobe seizures, or generalized
epilepsy. Approximately 25% had EEGs to directly compare before and
after starting the carnosine. Many patients had reductions in
seizure frequency, but without EEG correlation. Two sisters with
hypsarrythmia/Lennox-Gastaut variant both showed dramatic
improvements in EEG amplitude, spike frequency, and background
activity. In three other patients with primary or secondary
generalized spike and wave patterns or Lennox-Gastaut type patterns,
EEG amplitude and spike frequency improved with carnosine in dosages
of 800-2,000 mg. per day. Dosage was titrated upward depending upon
bodyweight. No side effects were reported. Unexpectedly, parental
diaries showed a pattern of comments related to gains in cognitive
domains including language, alertness, energy levels, and even gross
motor ability. Dr. Chez was motivated by such reports in addition to
comments from other professionals that worked simultaneously with
the children (e.g., speech therapists) who, unaware that children
were on the new supplement, spontaneously stated that individual
children were showing incremental gains not previously seen.
Expressive language was described as more fluent, eye contact more
frequent, and interest in the environment was more prominent. Dr.
Chez thought that this supplement could be of benefit to children
with autism or PDD and so began to give it to children with such
diagnoses in an open-label trial.
Indeed, parents reported benefits in their children after as few
as 2 weeks, in the areas of socialization, expressive language,
alertness level, energy level, adaptation to change, and curiously,
gross motor planning.
The Double-Blind Study Because of the remarkable
cognitive improvements in language, speech production and school
performance as well as social alertness, Dr. Chez felt it important
to study the effect of the supplement in children with Autistic
Spectrum Disorders. Children were included in this study if they had
histories of abnormal EEG, and had previously responded to
cognitive-enhancing dementia medications (as part of a controlled
study at the office) or to anti-convulsants. A double-blind placebo
controlled study with carnosine was begun. Children were randomly
placed on either active carnosine or placebo. Expressive and
receptive language measures, two autism rating scales, and parent
rating analog scales were administered at the start and completion
of the study. Results of this study indicated clinically meaningful
changes in many aspects of autistic features, and also showed that
the carnosine supplement improved children's expressive and
receptive language significantly. This is the only dietary
supplement to date studied in a double-blind fashion in autism.
Who Benefits and What are the Side Effects? The
majority of children with either epilepsy or autism treated in open
label studies by Dr. Chez benefitted from carnosine supplementation.
Dr. Chez estimates that approximately 10% of children who have been
on the carnosine supplement have had reports of no improvement. A
very small percentage (less than 5% of children with epilepsy or
autistic spectrum disorders) have shown increased physical
hyperactivity or verbal hyperactivity, but we are unable to
ascertain if these reports are directly related to the carnosine
supplement. No sleep disturbances were reported as a result of
carnosine therapy even in dosages up to 3,000 mg. a day. No
abdominal side effects, skin rashes, or any changes in
anticonvulsant blood levels, liver functions or hematological
studies. No patients had any urinary changes or bowel habit changes
from the carnosine. Many children on the autistic spectrum were
reported to increase their range of food choices with an improved
range of appetite. Responses have been seen in generalized
epilepsies, focal seizure disorders, autism, PDD, and head injury to
date. Because of its effect on entorhinal cortex, improvements in
Alzheimer's disease or other frontal lobe encephalopathy may be
possible. Any syndrome that involves apraxia or expressive language
delay may benefit from this. Concurrent studies are currently being
run or planned in areas of attention disorder, Tourette's syndrome,
and various learning disability syndromes of the nonverbal type.
What is Carnosine? The supplement that you are
interested in learning more about contains 200mg powdered carnosine,
as well as powdered Vitamin E (25IU) and powdered Zinc (2.5 mg). The
exact dosage that is correct for your child should be established by
your doctor in coordination with Dr. Michael Chez, who pioneered the
use of this supplement in children with developmental delays. L-carnosine,
or "carnosine" is an amino acid dipeptide made up of histidine and
alanine. The naturally-occurring amino acid is found within the
human body, a by-product of proteins digested within the body. The
deep frontal part of the brain (entorhinal cortex) is believed to be
a site where carnosine tends to accumulate. It may interact with
zinc in that area, as well as having effects on GABA, a brain
neurotransmitter, which by a complex chemical reaction forms homo-carnosine.
What Studies Have Been Done with Carnosine? Rat
and animal studies have been done with carnosine looking at "neuroprotection."
These investigations aimed to examine protective function. There
have been no studies that have shown any evidence of toxicity or
teratogenicity in animals where carnosine has been studied. Few
scientifically-validated human studies have been conducted, however,
and most of the information one finds about carnosine's claims are
of the quality found on the intenet. Claims have been made for
generic carnosine/carnosine formulations aiding in combatting a
range of maladies from Alzheimer's to body building.
Recent MRI studies by Petroff and colleagues (2001) examining
levels of brain chemistry showed a relationship between
homo-carnosine and GABA in temporal lobe and generalized myoclonic
epilepsies. These authors described homo-carnosine levels that may
correlate with seizure control even when GABA response is defective
in human studies. Dr. Chez was intrigued by the results of this
study, and thus began a study in June, 2001 that aimed to test if
supplementing carnosine orally could enhance seizure protection in
children who were already on anticonvulsants and who had recurrent
seizures despite being on standard drug therapy. He hypothesized
that the addition of carnosine could decrease seizure frequency and
so began an open-label study of carnosine which he acquired via an
industrial chemical company.
Dr. Buttar’s Clinic, Advanced Concepts in Medicine, the Center
for Advanced Medicine, specializes in the treatment of cancer,
cardiovascular and neurodegenerative disease in patients who have
failed conventional medical treatments. The clinic has also
attracted international patients suffering from various other
chronic diseases as well as “difficult to diagnose” medical
conditions from all over, including Africa, Europe, Central/South
America, Australia and Asia.
To see the four part series click on the links below. To
return here press the back button on your browser after each part.
Note: The above link will take
you to the Center for Advanced Medicine and Clinical Research
website. To return here press the back button on your browser.
This program contains the information from Dr.
Buttar s seminar used to educate patients on heavy metal toxicity
and the impact on chronic disease. 8 out of 10 deaths in the US are
due to cancer and/or heart disease. This is especially disturbing
when considering both heart disease and cancer have been clearly
associated with chronic heavy metal toxicity. Other chronic diseases
associated with heavy metals include stroke, vascular disease,
neurodegenerative conditions, autoimmune diseases, fibromyalgia, and
a host of other medical conditions.